An interview was given to BioInform upon their request on SIMAP and
Compugen & Aureus role in the project. An article was published in
the same journal afterwards.
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Functional analyses and Molecular modeling of two c-Kit mutations
responsible for Imatinib secondary resistance in GIST patients.
Tamborini E, Pricl S, Negri T, Lagonigro ML, Miselli F, Greco A,
Gronchi A, Casali PG, Ferrone M, Fermeglia M, Pierotti MA,
Pilotti S.
Oncogene, 2006, 25: 6140-6 (INT)
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the article
c-Kit/PDGFRA Gene Status Alterations Possibly Related to Primary
Imatinib Resistance in Gastrointestinal Stromal Tumors.
Francesca Miselli, Paola Casieri, Tiziana Negri, Marta Orsenigo, M.
Stefania Lagonigro, Alessandro Gronchi, Marco Fiore, Paolo G. Casali,
Rossella Bertulli, Antonino Carbone, Marco A. Pierotti, Elena Tamborini
and Silvana Pilotti
Clin Cancer Res. 13 2369 (2007).
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the article
A sporadic multiple GIST with unusual pathological, molecular and
genetic features
Miselli F, Conca E, Casieri P, Grosso F, Schiavo M, Tamborini E,
Pilotti S.
Am J Surg Pathol. 32, 340 (2008).
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the article
Transcriptomal profiling of site-specific Ras signals
Agudo-Ibanez L., Nunez F., Calvo F., Berenjeno I.M, Bustelo X.R.,
and Crespo P. "Transcriptomal profiling of site-specific Ras
signals". Cell. Signal.., 19, 2264-2276. (2007).
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the article
Regulation of MAPKs by growth factors and receptor tyrosine kinase.
Katz M, Amit I and Yarden Y. (2007)
Biochim. Biophys. Acta: (Epub ahead of publication)
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the article
Role of Non-phosphorylated Activation Loop Residues in Determining
ERK2 Dephosphorylation Activity, and Subcellular Localization
Bendetz-Nezer, S., and R Seger, R. (2007)
Role of non-phosphorylated activation loop residues in determining
ERK2 dephosphorylation, activity, and subcellular localization.
J. Biol. Chem. (2007), 282, 25114-25122.
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the article
Calcium-mediated interactions regulate the subcellular localization of
extracellular signal-regulated kinases (ERKs)
Chuderland, D., Marmor, G., Shainskaya, A., and Seger, R. (2007).
J. Biol. Chem. (2008)
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Compugen Profile- As appeared in "Future Magazine":
Compugen's mission is to be the world leader in the discovery and
licensing of product candidates to the drug and diagnostic industry. The
Company's powerful discovery engines enable the predictive discovery
of numerous potential therapeutics and diagnostic biomarkers.
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Role of Non-phosphorylated
Activation Loop Residues in Determining ERK2 Dephosphorylation,
Activity, and Subcellular Localization
Sarit
Bendetz-Nezer and Rony Seger
From the
Department of Biological Regulation, Weizmann institute of Science
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space
SH2B1b
adaptor is a key enhancer of RET tyrosine kinase signaling
S Donatello, A
Fiorino, D DeglfInnocenti, L Alberti, C Miranda, L Gorla,
I Bongarzone, MG
Rizzetti, MA Pierotti and MG Borrello
Department of
Experimental Oncology, Research Unit no. 3, Milan, Italy; Department of
Experimental Oncology, Research Unit no. 4, Milan, Italy; Scientific
Direction, IRCCS Istituto Nazionale Tumori Foundation, Milan, Italy and
FIRC Institute of Molecular Oncology Foundation, Milan, Italy
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Space
SBMLeditor: effective creation of models in the Systems Biology Markup Language
(SBML)
Nicolas Rodriguez , Marco Donizelli and Nicolas Le Novère
European Bioinformatics Institute, Wellcome Trust Genome Campus,
Hinxton, Cambridge, UK;
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